Seattle Genetics is a leading biotechnology company, founded in 1998, that specializes in the development of antibody drug conjugates (ADCs) that work to kill cancer cells. These antibody-based therapies are created in conjunction with ADC and SEA technology. The company produces FDA approved products that are commercially available in 47 countries and counting. They address unmet medical needs through a robust product pipeline. As of July 2016, Seattle Genetics announces that their product, ADCETRIS, is the first in a new class of ADCs and, in collaboration with Takeda Pharmaceutical Company Limited, is commercially available in 65 countries. As of now, the drug is being conducted in a broad clinical development program evaluating its potential to become the foundation of treatment for CD30-expressing lymphomas. In August 2016, Seattle Genetics announced positive data from phase 3 ALCANZA clinical trial of ADCETRIS for CD30-expressing cutaneous T-cell lymphoma. The company is publically traded, SGEN. As of June 30, 2016, the company has $659.5 million in cash and investments. The company also has 140 million common stock outstanding.
Clay Siegall is the co-founder, president and CEO of Seattle Genetics in 1998 located in Bothell, WA. He is presently a Chairman of the Board and has been there for 18 years. He has built the company into a leader and innovator of the biotechnology worlds through its multiple strategic licenses for its ADC technology that include Genentech (Roche), AbbVie, GlaxoSmithKline, and Pfizer. These have spawned more that $300 million to date. In addition, Seattle Genetics collaborates with both internal and external programs that amount to more than 20 ADCs in clinical development.
Siegall studied at the University of Maryland and obtained a Bachelor of Science (B.S.) in Zoology and then a Doctor of Philosophy (Ph.D.) in Genetics at The George Washington University. Before working for Seattle Genetics, Dr. Siegall worked for Bristol-Myers Squibb Pharmaceutical Research Institute from 1991 to 1997 and the National Cancer Institute, National Institutes of Health from 1988 to 1991. Currently, he resides on the Board of Directors for three companies; Ultragenyx Pharmaceutical for 2 years, Mirna Therapies, Inc. for 3 years and Alder Biopharmaceuticals Inc. (Nasdaq: ALDR) for 10 years. Mirna and Alder BioPharmaceuticals are both private biotechnology companies.
He has received Entrepreneur of the Year for Pacific Northwest Ernst and Young in 2012 as well as Alumnus of the Year for Computer, Math and Natural Science at the University of Maryland in 2013.